PRP Survival Guide


Issues related to itching and itch relief

The PRP Survival Guide is a repository of experiences and insights shared by PRP patients and their caregivers. Collectively, the PRP community possesses a wealth of practical knowledge about pityriasis rubra pilaris. We need to harvest that knowledge for those in need of enlightenment. Share what you have learned about PRP as a patient or caregiver. Share what you have been told by your dermatologist? Share articles  you feel might be worth reading or websites worth visiting.

If you have anything to share on the subject of ITCHING and ITCH RELIF, please use the  “Editor” link to share.

From MedlinePlus

Itching is skin tingling or irritation that makes you want to scratch the itchy area. It’s a symptom of many health conditions. Common causes are:

✽  Allergic reactions ✽  Eczema ✽  Dry skin ✽  Insect bites and stings ✽  Irritating chemicals ✽  Parasites such as pinworms, scabies, head and body lice ✽  Pregnancy ✽  Rashes ✽  Reactions to medicines

Editor’s Note: I guess pityriasis rubra pilaris falls into the category of uncommon causes.

Itch Relief

To soothe itchy skin, you can try cold compresses, lotions and lukewarm baths. Avoid scratching, wearing irritating fabrics and high heat and humidity. Most itching is not serious. However, if you itch all over, have hives that keep coming back or have itching without an apparent cause, you might require medical attention.

From American Academy of Allergy, Asthma & Immunology


Itching can be caused by many different things including allergies, insect bites, dry skin or illness.

While most itches are merely bothersome or uncomfortable, excessive scratching can damage your skin’s protective barrier and expose your body to germs and infection.

Itch and pain are closely linked in the brain. The reflex to pain is to withdraw. The reflex to itch is to scratch. This reflex is a protective response developed to help animals remove parasites from their skin. That’s why even a slight movement of hairs is enough to make you want to scratch.

Itching is often triggered by histamine, a chemical in the body associated with immune responses. It causes the itch and redness you see with insect bites, rashes and skin dryness or damage.

Histamine is released by the body during allergic reactions, such as those to pollen, food, latex and medications.


Pruriceptive itch is due to an allergic reaction, inflammation, dryness or other skin damage. It is seen in atopic dermatitis (eczema), urticaria (hives), psoriasis, drug reactions, mites and dry skin. This type of itch is often treated with antihistamines and other drugs that alter the immune reaction.

Neuropathic itch is caused by damage to the nervous system. It is usually accompanied by sensations of numbness and tingling. This type of itch is seen after shingles, after stroke or burn injury, and in notalgia parasthetica (an area of itchy skin, usually on the back). It is treated with non-narcotic analgesics and capsaicin.

Neurogenic itch is seen in chronic liver and kidney disease in response to opioid neuropeptides. It is treated with narcotic and non-narcotic analgesics.

Psychogenic itch is induced in response to the chemicals serotonin and norepinephrine. These chemicals influence stress, depression and delusional parasitosis (a false belief of parasite infestation). Psychogenic itch is treated with antidepressants and antipsychotic medications.

An allergist / immunologist has advanced training and experience to identify what is triggering a persistent or reoccurring itch and to prescribe treatment.

Edited feedback from members of the PRP Facebook Support Group. re: Pain and Itch

Tierney R — Virginia Beach, Virginia; March 9, 2019 (34 comments)



Posted by: Isabell May — Melbourne, Victoria, Australia; January 26, 2019 (29 comments)

“Does anyone take anti-histamines to relieve the itch?”