What do I need to know about methotrexate?

Why is methotrexate prescribed?

Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments. Methotrexate is also used along with rest, physical therapy, and sometimes other medications to treat severe active rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) that cannot be controlled by certain other medications. Methotrexate is also used to treat certain types of cancer including cancers that begin in the tissues that form around a fertilized egg in the uterus, breast cancer, lung cancer, certain cancers of the head and neck, certain types of lymphoma, and leukemia (cancer that begins in the white blood cells). Methotrexate is in a class of medications called antimetabolites. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis by decreasing the activity of the immune system. Brand names include: Rheumatrex® and Trexall®. Other names: Amethopterin and MTX

Click HERE to learn more about methotrexate at MedlinePlus (U.S. Library of Medicine)


One Reply to “What do I need to know about methotrexate?”

  1. June 2017.
    I have been on MTX since Nov 2016. 25 mg weekly combined with Folic 1 mg on those days I don’t take MTX. Has it helped me ? Honestly I don’t know for I have also been having phototherapy sessions 3 times a week since March 2016. Both treatments try to prevent/slow down the growth of skin cells so I don’t know which one has helped my skin condition.
    As to side effects, I am wiped out, tired , needing an afternoon nap, etc the day after I have taken MTX.

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